Research

Shore Medical

Clinical Research is a core function of the NHS which helps drive innovation and maintain high standards of patient care. Shore Medical takes part in research commissioned by the NHS which enables us to offer our patients access to new and improved treatments, interventions and medicines which ultimately helps us to develop a wider evidence base across primary care. Dr Alex Todd is our Research Lead at Shore Medical and has completed Good Clinical Practice for Research (GCP) training to ensure we comply with principles set out by the UK policy framework for health and social care research.

The Department of Health set up The National Institute for Health and Research (NIHR) to fund, enable and deliver world-leading health and social care research to improve people’s health and wellbeing and promote economic growth. At a local level the Wessex Clinical Research Network (CRN) provides infrastructure and support to promote high quality research across our area.

There are a number of ways in which you can become involved in research studies within Shore Medical. A doctor or nurse may talk to you about a particular study relevant to your health and ask whether you would be interested in taking part, you may be sent information by SMS or through the post if you are identified as a suitable participant or you may read about studies on our website or in our waiting room.

The studies we undertake have been reviewed by the Wessex CRN and have had ethical approval to ensure they are safe to perform. Your participation is entirely voluntary, and you can withdraw from a research study at any time. Your care will not be affected in any way should you decide not to take part. The consent process ensures you receive clear information about what taking part would involve and you would have the opportunity to ask questions and obtain further details.

For further patient information please visit the NHS Health Research Authority website: Patient Data and Research leaflet – Health Research Authority (hra.nhs.uk)

REGAIN Trial:

Shore Medical is assisting with the REGAIN trial as a patient identification centre (PIC).

This REGAIN study aims to find out which of two treatments is better for helping people recover after being in hospital with COVID-19:

  • An online-rehabilitation exercise and recover support group OR
  • A single online session of exercise advice and support

Please visit: REGAIN Trial (warwick.ac.uk) for further information.

COVID MONITOR – monitoring for side effects after booster vaccine:

Shore Medical is assisting with the COVID MONITOR trial as a patient identification centre (PIC).

A study run by the Drug Safety Research Unit (DSRU). Patients are eligible to register via the website within 48 hours of having their Covid booster. The study then involves completing 7 brief questionnaires over the course of 6 months. This will help build up data about potential side effects from the booster vaccinations. We will also be handing out leaflets for this study during our Shore vaccine clinics.

www.covidvaccinemonitor.eu/uk-booster

PANORAMIC Trial

Shore Medical is assisting with the PANORAMIC trial as a patient identification centre (PIC).

COVID-19 has affected the lives of everybody. We need to find safe and effective treatments that can help people to recover at home, without the need to go to hospital.

Researchers at the University of Oxford – in partnership with the NIHR – are trying to do this right now, and you have an opportunity to help by joining a national priority study called PANORAMIC.

The trial aims to find antiviral treatments that reduce hospital admission and speed-up recovery for people with COVID-19, who are at home and in the early stages of infection.

The first antiviral treatment to be investigated through the trial will be molnupiravir (brand name Lagevrio).

To take part, you will need to have had a positive COVID-19 test result and be experiencing COVID-19 symptoms which started within the last five days. You also need to be aged 50 years and over, or 18 years and over with an underlying health condition, such as asthma.

Taking part is easy. Eligible participants can join online or over the phone from the comfort of your own home. We will courier all the information you need directly to you at home. You will also receive a symptom diary, and you may receive a treatment to take.

Find out more and join the PANORAMIC trial’s volunteers in the search for COVID-19 treatments by visiting: https://www.panoramictrial.org/.

Clinical Practice Research Datalink (CPRD)

Shore Medical is signed up to CPRD, this is a real-world research service supporting retrospective public health and clinical studies. CPRD is jointly sponsored by the Medicines and Healthcare products Regulatory Agency and National Institute for Health and Research, as part of the Department of Health and Social Care. CPRD collects anonymised patient data from a network of GP practices across the UK. For more than 30 years, research using CPRD data and services has informed clinical guidance and best practice, resulting in over 2,800 peer-reviewed publications investigating drug safety, use of medicines, effectiveness of health policy, health care delivery and disease risk factors. CPRD only receives and supplies anonymised patient data and complies with robust ethics, governance and security regulatory frameworks.

PRINCIPLE trial:

For those who have tested positive for COVID-19 infection in the last 14 days AND are unwell with symptoms – including, but not limited to, high temperature, new, continuous cough, loss or change to smell or taste, sore throat, shortness of breath, general feeling of being unwell, muscle pain, diarrhoea.  The PRINCIPLE trial aims to find treatments that improve symptoms and reduce hospital admissions. The study is currently looking at favipiravir (an antiviral drug) against usual standard NHS care.

Please visit: www.principletrial.org or call 0800 138 0880 for further information.

COV BOOST:

Shore Medical is assisting with the COV BOOST study by acting as a Patient Identification Centre (PIC). Their study is looking at seven different COVID-19 vaccines when given as a third dose and is supported by the National Institute for Health Research (NIHR). Adults who are aged 18-30 who have had 2 doses of Pfizer or Moderna at least 3 months apart who have not received a booster may be eligible to take part, further information is available on their website:

Participate – University Hospital Southampton NHS Foundation Trust | COV-Boost (covboost.org.uk)

Active Studies

  • REGAIN Trial
  • COVID Monitor
  • PANORAMIC Trial