Research

Updated March 2025

Clinical Research

Clinical Research is a core function of the NHS which helps drive innovation and maintain high standards of patient care. Shore Medical takes part in research which enables us to offer our patients access to new and improved treatments, interventions and medicines which ultimately helps us to develop a wider evidence base across primary care.

Dr Alex Todd is our Research Lead at Shore Medical and he is supported by the Research Team which includes dedicated research nurses and a Research Operations Lead. Everyone working on Research Studies completes comprehensive research-specific training in addition to mandatory Good Clinical Practice for Research (GCP) training to ensure we comply with principles set out by the UK policy framework for health and social care research.

The Department of Health set up The National Institute for Health and Research (NIHR) to fund, enable and deliver world-leading health and social care research to improve people’s health and wellbeing and promote economic growth. At a local level, Shore Research works with the South West Central Research Delivery Network (RDN) which provides infrastructure and support to promote high quality research across our area. The NIHR Primary Care Strategy clearly outlines how to promote and facilitate high quality research within the Primary Care setting. (NIHR Clinical Research Network Primary Care Strategy 24 Feb 2022 v1.0)

South West Central | NIHR RDN

In October 2025, The NIHR established 14 new Primary Care Commercial Research Delivery Centres (PC-CRDCs) across the country. The Adam Practice in Poole which has an established history of running clinical trials, was successful in being selected to host the Dorset PC-CRDC, in collaboration with five other GP practices within Dorset. Shore Medical is one of these practices.

The Dorset CRDC aims to make it much easier for our local population to take part in research and get access to treatments and technologies that previously they would only have been able to access in hospital settings.

By working together The Dorset CRDC will help more people across Dorset take part in research, increasing accessibility to all parts of our community.

Inclusive Research
We are committed to ensuring that people from all backgrounds have the opportunity to take part in research. The Dorset CRDC works to make research accessible and relevant to the diverse communities we serve.

How We Work Together
The practices working within the Dorset CRDC are committed to embedding research into routine care. Not every practice has all the facilities or staff required to run every type of study, so by working together we share resources across different sites to ensure more studies can be delivered locally.

What This Means for People Invited to Take Part
Depending on the requirements of the study, visits may take place at your local practice or at another location. This may be one of the other collaborating practices or The Adam Practice at the Upton Surgery.
Your name may be identified through a database search run by your practice as being potentially suitable for a particular study. If this happens, you may receive information about a study from your practice research team by telephone to ask if you are interested in taking part. This may be followed up with a text or email. You may also be sent information about a study that requires you to actively register your interest on a secure website (“landing platform”) if you would like to take part.

Your Choice and Your Information
Taking part in research is completely voluntary. You will be provided with information about the study, including the risks and benefits, via a study‑specific Patient Information Sheet so that you can make an informed decision. We encourage you to speak to family members or friends if you wish to discuss the study before deciding.

Some studies can only be conducted at practices with the necessary facilities required by the study sponsor. This means that some study visits may take place at one of the practices working together as part of the collaboration, which may not be where you are registered. If this is the case and you are interested in taking part, you will be asked for your consent to share your personal information with the practice where the study is being conducted. There are strict Data Protection rules in place to protect your information, which we adhere to at all times. Please ask if you would like further details.

If you do not wish to be contacted about research, please let the surgery know so this can be recorded on your medical record.

Please check the “Open Studies” tab for further details – studies run as part of this collaboration are marked with “Dorset Primary Care CRDC”

There are a number of ways in which you can become involved in research studies within Shore Medical;

  • The Research Team at the practice may look at your record to determine whether you are suitable to be invited for a research study. If you are identified as a suitable participant, a doctor or nurse may talk to you about a particular study relevant to your health and ask whether you would be interested in taking part.You may be sent information by SMS text, through the post or by email
  • You may read about studies on our website or in our waiting room
  • You can register an interest in becoming involved in research studies through the national Be Part of Research website, Be Part Of Research (nihr.ac.uk) 

The studies we undertake have all received approval from the Health Research Authority (HRA) to ensure they are safe to perform. If studies involve a new medication or a new medical device, then they will also have been approved by the Medicines and Healthcare products Regulatory Agency (MHRA). Your participation is entirely voluntary, and you can withdraw from a research study at any time. Your care will not be affected in any way should you decide not to take part. The consent process ensures you receive clear information about what taking part would involve and you have the opportunity to ask questions and obtain further details.

For research queries, please contact: research.shore@nhs.net or telephone the team directly on 01202 545195

For further patient information please visit the NHS Health Research Authority website: Patient Data and Research leaflet – Health Research Authority (hra.nhs.uk)

Updated June 2026

Open Studies

Easi-KIDNEY Study

Some people with kidney disease develop heart problems or will progress to require longterm dialysis or transplantation. The Easi-Kidney study is an international study investigating a new treatment in combination with the well tested treatment empagliflozin to slow the progression of Chronic Kidney Disease (CKD) and prevent problems such as heart failure and dying of cardiovascular problems.

Open: May 2026
Enrolment Ends: 2026
Study Duration: 3-4 Years

AMAZE-1 Study (Dorset Primary Care CRDC)

This study is investigating the effects of a new injection on weight loss. Patients will remain on treatment for 2-3 years.

Open: May 2026
Enrolment Ends: Sep 2026
Study Duration: 2-3 Years

MOVE Lp(a) Study (Dorset Primary Care CRDC)

Lipoprotein (a) is also known as Lp(a). Lp(a) is an important risk factor for heart disease and is largely determined by your genes. Lp(a) carries cholesterol in your blood. If you have high Lp(a), you may have a higher risk for heart disease or stroke.

The MOVE Lp(a) study will test if an investigational medicine safely lowers Lp(a) levels and reduces the risk for heart disease or stroke.

Open: Jan 2026
Enrolment Ends: 2027
Study Duration: 5 Years

Patient Identification Centre (PIC Site)

Patient Identification Centres (PICs) identify patients who may be eligible for a clinical trial and refer them to a designated research site for recruitment and study procedures. Their primary role is to expand access to trials by connecting potential participants to other research teams. Shore Medical acts as a PIC for some academic research studies which are conducted at other research centres across the country.

Studies open where Shore Medical is a PIC site;

CORAL
Coenzyme Q10 (CoQ10) is a nutrient sold as a supplement in many chemists & health food shops. It is naturally found in food such as meat, fish & nuts.

Some studies have shown that CoQ10 might benefit people with heart failure. Heart failure is a long-term condition where your heart can’t pump blood around the body properly, and can affect quality of life and how people function day-to-day.

The CORAL study will try to find out if C0Q10 is a helpful treatment and whether it should be prescribed to people with heart failure.

Phone calls take place by the Bristol research team and the medication will be posted to patients.

http://www.coral-study.bristol.ac.uk/

Brief Study summaries Shore website

SAFE-D (PIC)

Pancreatic cancer is often detected when it is at an advanced stage and very difficult to treat successfully. Early diagnosis is therefore key for better survival rates. Patients recently diagnosed with type 2 diabetes have a higher-than-normal risk of developing pancreatic cancer. There is currently no approved screening test for pancreatic cancer. SAFE-D is a study that aims to show how well a new test (the Avantect test) works on early detection of pancreatic cancer in individuals with early signs of or newly diagnosed with type 2 diabetes.

Visits take place at a Dorset Research Hub.
www.safe-d.uk

CARE-UK

The CARE-UK is looking to identify whether children with asthma aged between 6-11 years, would be interested in trying out a combination reliever inhaler. Study visits would take place at Bournemouth Hospital.

https://careukstudy.uk/

Studies closed to recruitment but still ongoing

AZURE-LDL Study

The study drug under investigation is called a PCSK-9 inhibitor. These drugs block a protein made by the body called PCSK-9. PCSK-9 increases the “bad” cholesterol (LDL) in the blood. By blocking this protein, this may help to reduce LDL and protect cardiovascular health.

TIGER

This study is looking at whether dietary advice based on food allergy tests improve disease control compared with standard of care in young children with eczema (aged 3 months to 2 years).

www.bristol.ac.uk/eczema-allergy-study

RCGP Research & Surveillance Centre Practice

This practice is one of over 1900 practices in England and Wales contributing pseudonymised data for national research and surveillance. This data enables continuous monitoring of infections and diseases in the community and is used in ethically approved research. The Oxford RCGP RSC is the main source of information for the UK Health Security Agency (UKHSA) and helps with prediction and management of flu outbreaks and pandemics. Providing pseudonymised data does not affect patients, their care or privacy, however if you no longer wish to allow your information to be used please speak to your GP.

Other Research Projects

Bowel Cancer Screening Pilot (Self-referral FIT Kit service)

Shore Medical are working with Dorset ICB and the Wessex Cancer Alliance on a pilot project looking to invite patients who are registered at Shore, who may have noticed a change in bowel habits. The pilot is only open to patients aged 40-49 years old. Patients within the age group will be sent a text inviting them to complete a questionnaire about any possible changes or symptoms they may have. The pilot project will run from April – Sept 2026.

Results from Previous Studies

We will post updates and/or results from studies we have worked on in the past, as and when this data becomes available to us.

With larger studies, results may not be published for several months after the last participant has finished their last involvement in the study.

If you are interested in finding out any further information about any of our studies, or simply would like to ask us what is involved in taking part in research, please contact the Shore Research Team at Lilliput on 01202 545195.

Further information about research and what projects are open to recruitment across the UK can be found in the below links;
Take Part – Take Part
Homepage | NIHR

Taking part in research is always voluntary, but discovering new treatments and medication, how they work and what works best, cannot progress without the valuable contribution of our patients. Thank you to all those who take part.

Clinical Practice Research Datalink (CPRD)

Shore Medical is signed up to CPRD, this is a real-world research service supporting retrospective public health and clinical studies. CPRD is jointly sponsored by the Medicines and Healthcare products Regulatory Agency and National Institute for Health and Research, as part of the Department of Health and Social Care. CPRD collects anonymised patient data from a network of GP practices across the UK. For more than 30 years, research using CPRD data and services has informed clinical guidance and best practice, resulting in over 2,800 peer-reviewed publications investigating drug safety, use of medicines, effectiveness of health policy, health care delivery and disease risk factors. CPRD only receives and supplies anonymised patient data and complies with robust ethics, governance and security regulatory frameworks.